The highway is an important connectivity route linking the provincial capital, Quetta, with Karachi, Pakistan’s largest city and commercial. A major explosion destroyed a bridge on the Quetta-Karachi National Highway, halting traffic and highlighting security concerns amid ongoing insurgency by Baloch separatist groups. BLA's coordinated attacks in Balochistan destroyed multiple bridges and shut down the Quetta-Karachi highway, causing major traffic disruption. Authorities imposed an indefinite curfew in.