Annie Andrews is projected to defeat Darline Graham, who was handpicked by President Trump to take her brother's seat after his death. President Trump handpicked Darline Graham to take over the seat held by her brother, influential Senator Lindsey Graham, after his death. In 2020, incumbent Republican Lindsey Graham won the Senate race in South Carolina with 1,369,137 votes (54.4%), defeating Democrat Jaime Harrison, who received 1,110,828 votes (44.2%).